JetMixer™ System

The JetMixerTM System provides fast powder mixing and complete protection of powder properties.

The efficient mixing of powders into liquids is a crucial step in profitable biopharmaceutical manufacturing. For operations where low shear and high product integrity are required, no other technology performs as well as the JetMixer™ System from ILC Dover. JetMixer™ consists of a few cleverly-designed, elegantly-simple components. A lobe-type, positive-displacement pump typically provides the driving force needed for operation. With its one moving part, the pump remains easy to clean, simple to maintain, and long-lived. In addition to the standard compact, mobile, and fixed skid-mounted forms, JetMixer™ can be easily configured to conform to dust-free process environments. It can be supplied with components fully compatible with nitrogen blanketing and other inert-gas protection protocols, as well as jacketing suitable for heating or cooling, depending on process requirements. For powders that clump or aggregate, we offer rotating comb systems for fluidization or our JetBreaker™ delumping system. For particles in suspension, homogenizers can be calibrated to produce specific final particle sizes.

Specifications

Patented Venturi/Nozzle System

The patented JetMixer^TM nozzle system creates a flat accelerated jet that draws a surprising amount of powder into the liquid stream without introducing clumping, shearing, or heating. The hopper system and constant level of venturi-generated vacuum assure particle-by-particle induction and mixing, even with high-viscosity fluids. The system works equally well for mixing solid suspensions into liquids or for liquid-liquid mixing. In all cases, the components are uniformly mixed to form a homogeneous fluid.

System Components

The venturi system and mixing chamber contain no moving parts while featuring smooth, polished flow channels and a lack of crevices, edges, or other impediments to WIP/CIP operations. Its inherently smooth geometry makes the system particularly suited for biopharmaceutical processes where CIP is a must and cross-contamination can imperil large amounts of high-value product. The all-stainless-steel system is robust, capable of operating at very low vacuum and process temperatures to 70°C (158°F).

Auxiliary Equipment

Where powders to be mixed tend to clump or aggregate, ILC Dover offers its JetBreaker^TM homogenizers that can delump powders and continuously agitate the hopper to improve flow rate and normalize injector feeding.